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Louise McCullough : ウィキペディア英語版 | Louise McCullough
Louise McCullough M.D., Ph.D is a practicing vascular neurologist and associate professor who is actively engaged in stroke research at the University of Connecticut Health Center (UCHC) in Farmington, Connecticut in the United States. She provides neurological care at both the John Dempsey Hospital in Farmington, CT and the Hartford Hospital in Hartford, CT, which has a state-of-the-art stroke center (). She is the director of stroke research at the department of neurology and neuroscience at UCHC and participates in teaching, research, medicine, and graduate student mentoring. ==Research== Dr. McCullough is perhaps best known for her research identifying gender-based differences in cell death pathways during cerebral ischemia using neuronal nitric oxide synthase (nNOS) and poly ADP ribose polymerase-1 (PARP-1) knockout models which was published in the ''Journal of Cerebral Blood Flow & Metabolism'' (2005). This paper was relevant as PARP-inhibiting drugs are currently undergoing clinical trials in a variety of pathologies. Her current research is aggressively investigating the differences in cell death pathways as well as regulation of energy utilization during cerebral ischemia.
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